Updates & Changelog

AI moves fast, and this guide evolves with it. This page tracks major updates, new modules, and significant revisions. Check back periodically to see what's changed.

v1.3 — March 2026

New Content

• AI News — 18 new stories covering GPT-5.4, HIMSS 2026 agentic AI theme, Doctronic jailbreak, Perplexity Comet browser exploits, RecovryAI FDA Breakthrough, Claude Sonnet 4.6, Gemini 3.1 Pro, Meta Llama 4, athenahealth free ambient scribe, Nabla vs DAX RCT, DeepSeek V4 controversy, AI chatbots and mental illness, and more

Module Updates

• OpenClaw — Major refresh: ClawHavoc supply chain attack escalation (1,184+ malicious skills), new critical CVEs (CVSS 9.8), 42,000 exposed servers, Steinberger joins OpenAI, open-source foundation, broader agentic AI threat landscape
• The Big Three — GPT-5.4 launch, Claude Sonnet 4.6, Gemini 3.1 Pro, Meta Llama 4, DeepSeek V4 controversy. Updated comparison table context windows.
• Clinical Decision Support — RecovryAI FDA Breakthrough, Mount Sinai LLM misinformation study, Doctronic jailbreak
• Ambient AI Tools — athenahealth free scribe, Nabla vs DAX RCT (72K encounters), Dragon Copilot 100K clinicians
• AI-Powered Search — Perplexity Computer (19-model orchestration), Comet browser zero-click security exploits, NotebookLM Gemini 3.1 Pro upgrade
• PHI, HIPAA, and AI — Doctronic SOAP note injection risk, HHS HTI-5 transparency rollback, DeepSeek data concerns, Comet file exfiltration
• Bias, Ethics, and Training Data — Mount Sinai misinformation study, AI chatbots worsening mental illness (Brown University), International AI Safety Report, updated FDA device counts
• When Patients Use AI Too — AI chatbot mental health crisis research, Doctronic and RecovryAI as contrasting patient-facing AI models
• Vibe Coding — GPT-5.4 computer use, Cursor JetBrains integration, Claude Code updates, Gemini Flash-Lite
• So...What Next? — Agentic AI goes mainstream (HIMSS), Llama 4 open-weight for local deployment, AWS Health AI agents, updated browser security warnings
• Start Here — NotebookLM Gemini 3.1 Pro upgrade with 1M context and PPTX export
• AI 101 for Medical Learners — AI chatbot mental health warnings, Doctronic example
• AI's Environmental Footprint — NVIDIA 70% healthcare AI deployment stat
• Glossary — Expanded “Agentic AI” definition

Site-Wide

• Bumped site version from v1.2 · 2026 to v1.3 · 2026 across all pages
• Updated card dates on homepage for all revised modules

v1.2 — February 2026

New Module

• OpenClaw — The viral AI agent that went from Clawdbot to Moltbot to OpenClaw in five weeks—and exposed why autonomous agents put your API keys, credentials, and patient data at risk. Includes curated resources from OX Security, CrowdStrike, Kaspersky, VirusTotal, Lex Fridman #491, and more.

New Content

• AI News — 14 new stories (Feb 3–16) covering the Pentagon vs Anthropic, the February model rush, Dr. Oz's AI avatar plan, GPT-4o retirement, GPT-5.3-Codex-Spark, Claude Opus 4.6, Perplexity Model Council, and more
• Vibe Coding “Something's Changed” — New section covering Claude Opus 4.6 (1M token context, agent teams), GPT-5.3-Codex-Spark (Cerebras chips), and the broader February 2026 model rush

Module Updates

• The Big Three — Updated for GPT-4o retirement, Claude Opus 4.6 with 1M token context and $30B funding round, Gemini reaching 750M MAU. Added February 2026 Update callout.
• So...What Next? — Added OpenClaw cross-reference in AI Agents section
• PHI, HIPAA, and AI — Added OpenAI Lockdown Mode for Healthcare and OpenClaw credential risk callout
• Clinical Decision Support — Added FDA January 2026 AI CDS guidance update
• AI-Powered Search — Added Perplexity Model Council launch callout
• Bias, Ethics, and Training Data — Updated FDA-authorized AI device count from 882 to 950+

Site-Wide

• Bumped site version from v1.1 · 2025 to v1.2 · 2026 across all pages
• Updated card dates on homepage for all revised modules

v1.1 — December 2025

New Modules

• So...What Next? — A comprehensive guide (~6,200 words) for learners who've completed the curriculum. Covers staying current, finding your niche, developer foundations (Git, command line, APIs), AI-powered development tools, AI agents, and practical first projects.
• AI-Powered Search — Answer engines, deep research tools, and knowing when to just Google it. Covers Perplexity, ChatGPT Search, Google AI Overviews, and medical-specific search considerations.

New Content

• 2025 AI landscape overview — Updated coverage of GPT-5/5.1/5.2, Claude Opus 4/4.5, Gemini 3, and DeepSeek releases
• AI Evaluation (Evals) deep dive — Why evaluation methodology matters for clinical AI deployment, core concepts, and learning resources
• AI Agents section — What agents are, healthcare use cases, risks and safety considerations, current technologies (n8n, LangChain, MCP)
• AI Browsers (Comet, Atlas) — Overview of agentic browsers with warnings about prompt injection and why they're not ready for clinical use
• Developer Foundations — Expanded tutorials on Git, command line, and APIs including step-by-step API key setup for OpenAI, Anthropic, and Google
• Tool deep dives — Detailed coverage of Cursor, Claude Code, and Codex with safety warnings about autonomous operation
• Lenny's Pass — Information about the newsletter subscription bundle that provides access to multiple AI tools

New Resources Added

• Simon Willison's Blog — Added to information diet recommendations
• AI Cred — Nate's resource to learn and test AI knowledge
• Your AI Product Needs Evals — Hamel Husain's introduction to evaluation
• Parlance Labs AI Evals Course — Comprehensive evaluation methodology
• GitHub, Codecademy, and freeCodeCamp learning resources for developer foundations
• Command line safety warning with link to cautionary incident

Module Updates

• The Big Three — Significant rewrite to focus on practical/structural differences rather than subjective quality claims. Added "Knowing Your Options" market context, "Just Pick One and Start" guidance, and "Evaluate With Your Own Use Cases" section. Removed claims about model "strengths" that shift with every update.
• AI Image and Video Creation — Updated with OpenAI's GPT Image 1.5 release (December 16, 2025). New model is 4x faster with improved text rendering, precise editing with facial likeness consistency, and new dedicated Images experience in ChatGPT sidebar.
• LLM Thinking — Added BMJ article on "Parallel pressures: the common roots of doctor bullshit and large language model hallucinations"
• Clinical Decision Support — Added "Semantic Drift" section featuring Dr. Olivia Milgrom's analysis of the OpenEvidence/oxacillin dosing incident
• Bias, Ethics, and Training Data — New module added to Foundations section
• When Patients Use AI Too — Enhanced with empathy-focused approach and expanded provider tools section
• Ambient AI Tools — Updated with 2025 research and current scribe landscape
• Everyday Ways to Use AI — Updated with 2025 tools and practical examples
• Vibe Coding — Expanded coverage of AI-powered development tools

Site Improvements

• Module update dates — Each topic card on the home screen now displays when it was last updated, helping you identify recently revised content
• Buy Me a Coffee — Added support button to About page for those who find the guide helpful
• Author bio — Added background information on the About page
• Contribute form — Wired up the contribution form for submitting suggestions and corrections

Fixes & Cleanup

• Fixed multiple broken links across PHI/HIPAA, Start Here, and other modules
• Removed outdated or non-functional resources (Two Minute Papers, Aitrepreneur, some Reddit communities)
• Updated NotebookLM tutorial link to current Google documentation
• Various typo and formatting corrections

v1.0 — November 2025

Initial Release

First public release of AI 101: A Self-Paced Guide to AI in Medicine.

Foundations Modules

• Start Here — Introduction using NotebookLM
• How LLMs Think Like Clinicians — Mental models for understanding AI
• PHI, HIPAA, and AI — Privacy considerations for clinical AI
• The Art of the Ask — Effective prompting techniques
• The Big Three — Guide to ChatGPT, Claude, and Gemini
• AI 101 for Medical Learners — Student and trainee-focused guidance

Using AI Modules

• Clinical Decision Support Tools — From UpToDate to OpenEvidence
• Ambient AI Tools — AI scribes in practice
• AI Image and Video Creation — Visual AI for healthcare
• Everyday Ways to Use AI — AI beyond medicine
• When Patients Use AI Too — Guiding patient AI use
• Vibe Coding — Building software without writing code

Resources

• AI's Environmental Footprint — Sustainability considerations
• Running AI Models Locally — Technical guide for local deployment
• AI Glossary & Learning Resources — Reference and further learning

Staying Updated

Bookmark this page and check back periodically to see what's new. You can also view the full commit history on GitHub.